Endocrine Abstracts

Introduction: During adrenal insufficiency (AI), glucocorticoid treatment is supposed to be neutral on the metabolic parameters of patients. However, recent data from the literature report that this corticosteroid replacement therapy increases the metabolic risk. The aim of our work was to determine the metabolic and cardiovascular impact of hydrocortisone (HC) replacement therapy during peripheral AI.Patients and methods: This was a descriptive and anal...

Introduction: Hydrocortisone (HC) is the most widely used replacement molecule in the treatment of adrenal insufficiency (AI). This substitution treatment is far from ideal especially as it is impossible to reproduce the nycthemeral cycle of cortisol with its current galenic form which has a short half-life. The aim of our work was to determine the impact of HC treatment of peripheral AI on the long-term quality of life and sleep.Patients and methods: Th...

Introduction: The treatment of adrenal insufficiency (AI) is based on long-term glucocorticoid substitution. Hydrocortisone (HC) is the most commonly used substitution molecule. The aim of our work was to determine the long-term bone impact of patients with peripheral AI.Patients and methods: This is a descriptive and analytical study involving 77 patients with peripheral IS (66 women and 11 men), all treated with HC. For each patient, we determined the ...

Introduction: Allowing to have a good glycemic control, presenting no contraindications and contributing to the optimization of the general and nutritional state, insulin remains a treatment of choice for the diabetic elderly. Proper injection technique is key to achieving and maintaining goal-level diabetes control. The objective of our study was to assess insulin injection techniques in elderly subjects with type 2 diabetes.Methods: A cross-sectional s...

Introduction: Management of diabetes in older adults is complicated by the many comorbidities that may interfere with the use of certain oral antidiabetic agents, and the associated geriatric syndromes, psychiatric disorders, and high risk of dependence in this age group. The objective of our study was to determine the factors associated with poor diabetes control in insulin-requiring elderly subjects.Methods: A cross-sectional study on type 2 diabetic i...

IntroductionCardiovascular disease is the leading cause of death ahead of infectious diseases and cancers. The frequency of morbidity and mortality associated with cardiovascular diseases increases in the elderly and their management becomes more difficult. Hence an early and adequate management of cardiovascular risk factors is needed. The objective of this work was to determine the cardiovascular risk factors in elderly diabetics and to assess the qual...

IntroductionThe metabolic syndrome (MS) presents a major public health problem, especially in elderly diabetics. The objective of this study is to assess the frequency and characteristics of MS in elderly diabetics.Patients and methodsRetrospective study of 94 diabetic subjects over the age of 65 years who were hospitalized in the endocrinology department of Mahdia or followed at the outpatient clinic between...

IntroductionDiabetes mellitus (DM) is one of the risk factors associated with severe illness in Coronavirus disease 2019 (COVID-19) leading to increased hospital admissions and mortality. COVID-19 can precipitate hyperglycemic emergencies like diabetic ketoacidosis (DKA) in patients with DM. We report 2 cases of diabetic ketoacidosis (DKA) secondary to COVID-19 with an atypical clinical picture mainly made up of neurological disorders without respiratory...

IntroductionThe prevalence of cardiovascular disease in the elderly is very important. The prevention of cardiovascular risk is essential in order to avoid the morbidity and mortality associated with these diseases. The objective of this study was therefore to assess the frequency of prescription of statins in elderly with diabetes and to analyze the benefit risk ratio of this prescription.Patients and methods<p class="abstext"...

IntroductionHadju Cheney syndrome (HCS) is a rare progressive and debilitating genetic disorder that is characterized by a high degree of phenotypical pleiotropy. We report the first clinical case of a 44-year-old patient with HCS, diabetes and adrenal insufficiency (AI).ObservationA 44-year-old patient with a history of myocardial infarction at the age of 33 and diabetes for 2 years on oral antidiabetic drug...